LumenI

---

LumenI is an instrument with a unique mix of optics and electronics which accurately analyzes the color of the conjunctiva and translates this precise color analysis into a reading of blood hemoglobin measured in grams per deciliter. 

LumenI emits a white light which illuminates the conjunctiva of the patient much like a physicians pocket flashlight. Optics in the LumenI focus the light reflected off of the conjunctiva, through an electronically controlled liquid crystal filter and onto a photodiode array detector. The output Voltage of the photo detector is digitized and sent to a microprocessor which digitally records the Voltage level. The different Voltage levels recorded across the visual spectrum are analyzed and the resulting hemoglobin level is calculated and displayed using calibration algorithms.

Using the basic design detailed above, Corum Medical is developing the family of LumenI products to meet the various needs of the specific market segments. The simple LumenI instrument described above might best be clipped into a shirt pocket while the instruments designed for use in blood banks might include a desk stand and additional accessories. The photograph above shows ongoing clinical evaluation of the technology concept while the photograph at right shows a mocked up prototype of LumenI design and operation. Initial trial results and more information can be found in the following publications:

-J.W. McMurdy , G.D. Jay, S. Suner, F.M. Trespalacios, and G.P. Crawford, "Diffuse Reflectance Spectra of the Palpebral Conjunctiva and its Utility as a Non-Invasive Indicator of Total Hemoglobin," Journal of Biomedical Optics 11 (1), 014019, (2006)

-J.W. McMurdy , G.D. Jay, S. Suner, and G.P. Crawford, "Anemia detection utilizing diffuse reflectance spectra from the palpebral conjunctiva and tunable liquid crystal filter technology," Proceedings of SPIE 6177 , 61771C1-10, (2006)

Users of LumenI are medical professionals involved in patient monitoring and screening. They include physicians, nurses, lab technicians, paramedics and first responders. The users will typically belong to an organization, such as a hospital, physicians practice, medical laboratory, EMS agency, or home nurses association

Preliminary market analysis indicates several distinct market segments for a non-invasive point-of-care (POC) Hgb measurement device. The segments differ in such factors as current use of Hgb tests, type of interaction with patients, need for reimbursement and other. While some segments appear to have similar characteristics worldwide, others will differ depending on the geography. Detailed market research will provide information for appropriate adjustments.

Analysis indicates that there may be a significant difference in value-based price levels between market segments. Blood banking segment has well understood economic benefits to switching to a non-invasive method, does not require reimbursement and can tolerate prices as high as $3K-$5K per device. At the same time, the physicians office market has a less pronounced fiscal benefit, does require reimbursement, and may have a lower price point to ensure best adoption and market penetration. Price differentiation between segments will be achieved with a set of segment-specific secondary features.